there's lots of stuff to bear in mind here.
weight. My Holden actually weight less that my MV6
tyres. DO NOT UNDER ANY CIRCUMSTANCES do anything which increases the hub height of the the tyre/wheel package. So, if you go for 18" wheels, then lower-profile tyres are a necessary. Actually, you're going along the right lines - decide on the size of brakes you need for the performance you have and then fit the wheels you need to clear the brake package.
I'd suggest that around 330 to 350mm discs are appropriate. But I might be wrong - I only have 20 years of brake designing experience.
I have three Omegas that may be of interest to you :-
Holden Commodore with 300mm discs ( eek ! ) twin-pot GM calipers - hopeless for the performance.
Opel Lotus Omega with 330mm discs ( really good brakes, but unreliable ) 4-pot AP calipers - think £2500 for a complete car's worth.
Opel Omega EVO 500, with a 350mm brake package that I've come up with (18" wheels required) reverse-engineered for about £250
whatever you decide to fit, then you need to have the package developed by a professional braking company, and by that I mean Bosch, Conti-teves or AP racing, and not a second-division outfit like EBC, or indeed anyone who would sell you a grooved or drilled disc.
Unfortunately, I don't carry the third-party insurance that would let me divulge the 350mm kit contents.