Did you check the condition of the spark plugs in cyl 1 and 4, i.e. are they oily? And are they in general good order?
Can you do a cylinder compression test to ensure it is not valve or head-gasket issue etc?
all new plugs in it...How do i do this - can you do a cylinder compression test to ensure it is not valve or head-gasket issue etc
The compression test is used to compare the compression between the cylinders. If one or more have significantly lower compression than the others, the reasons could be burnt or leaking valves, or worn compression rings. Adding a spoonful of engine oil into the plug hole and repeating the test will help identify the problem - if the compression rises following the oil addition then the problem is with the compression rings, if it does not then it is with the top part i.e. valves.
Other causes for low or no compression are wrong timing (though this would typically affect all cylinders), or blown head gaskets. If two adjacent cylinders have low compression, it is possible that the gasket has blown between the two cylinders.
The test is done by removing the fuel pump fuse and allowing the engine to idle and die out (you don't want fresh petrol flooding the cylinders and contaminating the cats), then removing all spark plugs, removing the HT leads to avoid spark, throttle fully open, stick the compression gauge into each plug hole one at the time and crank the engine a few times until the reading peaks.
If you have a screw-on compression gauge, as opposed to a press-on one, you can do it yourself and don't need a helper.
The reason for this test is that the engine needs four things (at the right time) to fire: fuel, air, compression, and spark. If one cylinder does not work, then it would typically be due to lack of any of the above....